Acute retroviral syndrome and high baseline viral load are predictors of rapid HIV progression among untreated Argentinean seroconverters

Table 3 Predictors of disease progression in untreated patients (unadjusted and adjusted analysis) (n = 92)

Risk factor	Unadjusted HR (95%CI)	p	Adjusted HR (95%CI)	p
Symptomatic PHI	1.41 (1.08- 1.83)	0.046	8.44 (0.97-73.42)	0.049
Age at seroconversion > 30 years	1.40 (0.93- 2.10)	0.159	4.42 (0.91-21.47)	0.065
Mode of HIV transmission (MSM)	1.38 (1.02-1.86)	0.081	0.99 (0.11-8.64)	0.995
Baseline CD4 cell count ≤ 350 cell/mm³	3.81 (1.64-8.86)	0.002	3.14 (0.47-20.78)	0.236
Baseline HIV RNA ≥ 100,000 copies/mL	1.91 (1.08-3.39)	0.043	9.44 (1.38-64.68)	0.022
HIV RNA at 6 months ≥ 100,000 copies/mL	9.88 (1.30-75.20)	0.008	2.24 (0.19-26.14)	0.520
Male sex	1.07 (0.89-1.29)	0.752	3.33 (0.16-67.54)	0.433
Year of diagnosis ≥ 2005	0.81 (0.61-1.09)	0.146	2.10 (0.20-21.99)	0.537