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Table 3 Factors associated with time to dropout or death among patients enrolled in the Limbe ART programme, Feb 2002-Dec 2005

From: Retention in an antiretroviral therapy programme during an era of decreasing drug cost in Limbe, Cameroon

   Complete Cases   Multiple Imputation
Characteristic n/N % Crude HR Adjusted HR Missing N(%) Crude HR Adjusted HR
    (95% CI) (95% CI)   (95% CI) (95% CI)
Age group        
   30+ 880/2081 42.3 1.00 1.00 116 1.00 1.00
   < 30 350/723 48.4 1.19 (1.03, 1.37) 1.20 (1.03, 1.43) (3.97) 1.22 (1.08, 1.34) 1.25 (1.10, 1.45)
Sex*        
   Female 760/1815 41.9 1.00 1.00 1 1.00 1.00
   Male 552/1104 50.0 1.20 (1.06, 1.36) 1.31 (1.14, 1.50) (0.03) 1.20 (1.07, 1.34) 1.33 (1.18, 1.50)
Occupation* 888/2044 43.4 1.00 1.00 170 1.00 1.00
   With some kind of income        
   Unemployed 316/706 44.8 1.04 (0.90, 1.20) 1.06 (0.91, 1.23) (5.82) 1.01 (0.89, 1.15) 1.03 (0.90, 1.19)
Marital status*        
   Married/living as 501/1166 43.0 1.00 1.00 143 1.00 1.00
   Never 558/1207 46.2 1.09 (0.96, 1.25) 1.10 (0.95, 1.27) (4.90) 1.14 (1.01, 1.28) 1.11 (0.98, 1.27)
   Previous marriage 158/404 39.1 0.85 (0.70, 1.04) 0.94 (0.76, 1.16)   0.91 (0.76, 1.09) 1.01 (0.84, 1.21)
Residence by distance to ART clinic*        
   Residents in Limbe 239/621 38.5 1.00 1.00 117 1.00 1.00
   Residents < 40 km from Limbe 339/801 42.3 1.13 (0.94, 1.37) 1.08 (0.89, 1.31) (4.01) 1.13 (0.96, 1.33) 1.05 (0.89, 1.23)
   Residents 40-150 km from Limbe 349/788 44.3 1.15 (0.95, 1.39) 1.13 (0.93, 1.36)   1.18 (1.00, 1.39) 1.12 (0.95, 1.32)
   Residents > 150 km from Limbe 236/454 52.0 1.63 (1.33, 2.00) 1.57 (1.28, 1.93)   1.52 (1.27, 2.51) 1.41 (1.18, 1.69)
   Residents from Douala, 74 km away*** 72/139 51.8 1.79 (1.33, 2.40) 1.71 (1.27, 2.30)   1.66 (1.28, 2.15) 1.51 (1.16, 1.98)
Means of payment for antiretroviral drugs*        
   Entirely paid by programme or employer 15/87 17.2 1.00 1.00 592 1.00 1.00
   Paid by self, family or partly by other 1036/2241 46.2 3.12 (1.67, 5.82) 3.34 (1.79, 6.25) (20.27) 2.95 (1.80, 4.85) 3.05 (1.99, 4.67)
Cohort        
   Enrolled after 1 Oct 2004 494/1433 34.5 1.00 1.00 0 N/A 1.00
   Enrolled before 1 Oct 2004 819/1487 55.1 1.04 (0.91, 1.19) 1.06 (0.92, 1.21) (0.0)   1.08 (0.96, 1.22)
Entry CD4 count (cells/mm 3 )*        
   > 100 543/1428 38.0 1.00 1.00 205 1.00 1.00
   0-99 644/1287 50.0 1.43 (1.27, 1.61) 1.41 (1.25, 1.61) (7.02) 1.43 (1.28, 1.61) 1.41 (1.27, 1.59)
  1. (complete case N = 2188; multiple imputation N = 2920).
  2. * Sample size smaller due to missing values
  3. ** Difficult access took into account the distance from ART centre as well as the presence of unpaved or poorly maintained road
  4. *** Patients residing in Douala with regular transport on paved roads and may have had other ART opportunities
  5. Abbreviations: ART (antiretroviral therapy)